"Ten Wanted Men" is the story of John Stewart (Randolph Scott) whose only crime was being friendly to Cornnie Michaels (Jocelyn Brando) when she needed it. Cornnie is the girlfriend of Wick Campbell (Richard Boone) a mean and rough land owner. Campbell doesn’t care for Stewart meddling in his affairs so he sets out and murders Howie Stewart (Skip Homeier), rustles Stewart’s cattle and even hires outlaws to come to the Stewart farm and shoot everyone. Campbell believes his men have killed everyone but Stewart survives and escapes only to return looking for vengeance on Campbell and his hired goons.