The master detective Sherlock Holmes (Basil Rathbone) and his faithful cohort Dr. Watson (Nigel Bruce) are back, preserved and digitally restored in 35mm to original condition by the UCLA Film and Television Archive. This newly restored version of the classic film includes the period war bond tag, studio logo, and credits from its original theatrical release. Filled with ominous shadows and interesting camera angles, the visual beauty of the film in 35mm is stunning.

London is in a panic over a series of apparent "Pajama Suicides." Sherlock Holmes, however, is more inclined to believe that they are calculated murders. It is up to the great detective to discover the motive and the means of these crimes and to unmask the murderer. Enter Miss Adria Seddig; an intoxicating woman of character whom Holmes is convinced is behind the killings. A series of masquerades and deadly game playing ensues as Holmes and Watson enter a battle of wits with the Spider Woman.