Disenchanted with the daily drudge of crushing rocks on a prison farm in Mississippi, the dapper, silver-tongued Ulysses Everett McGill (George Clooney, The Perfect Storm) busts loose. Except he's shackled to his two chain-mates from the chain gang - bad tempered Pete (John Turturro, Summer of Sam) and sweet, dimwitted Delmar (Tim Blake Nelson, Hamlet). With nothing to lose and buried loot to regain - before it is lost forever in a flood - the three embark on the adventure of a lifetime in this hilarious offbeat road picture. Populated with strange characters, including a blind prophet, sexy sirens and a one-eyed Bible salesman (John Goodman, Coyote Ugly), it's an odyssey filled with chases, close calls, near misses and betrayal that will leave you laughing at every outrageous and surprising twist and turn.