"The Big Bang" sees Ned Cruz (Antonio Banderas) a simple man turned private eye. Ned handles simple cases, a cheating spouse, a shady employee even those people who like to cheat insurance companies. He’s hired by Simon Kestral (Sam Elliott) to find a missing stripper named Lexie Persimmon (Sienna Guillory). This should be easy but quickly proves harder than it appears as Ned learns Lexie is the splitting image of Julie Kestral (Sienna Guillory) the wife of the old tycoon, Simon. Ned’s investigation takes him from the porn invested underbelly of Los Angeles to the New Mexico desert and straight into the pounding fists of Anton ‘The Pro’ Protopov (Robert Maillet), a Russian boxing champ. Ned also finds himself shadowed by three crooked cops, Frizer (Thomas Kretschmann), Skeres (Delroy Lindo) and Russell (Robert Ernie Lee) all who are looking for the same thing he is and systematically killing all of his witnesses. Ned quickly learns there is more to this than a simple kidnapping and a lot of money riding on something called The Big Bang!