A woman is taken on a voyage to the other side of sanity in this moody thriller. Dr. Miranda Grey ( Halle Berry ) is a clinical psychologist who works alongside her husband, Dr. Doug Grey ( Charles S. Dutton ), in the mental ward of a top security prison, where Miranda has been devoting much of her attention to a clever but deeply disturbed murderer named Chloe ( Penélope Cruz ), who shares gruesome tales of torture and violence that may or may not be based in fact. One night, Miranda has a hideous nightmare in which a chance meeting with a strange young girl leads to a terrifying journey into madness. Once she wakes, however, Miranda discovers that the real horror has just begun — Doug has been brutally murdered, and the evidence points to Miranda as the prime suspect. She soon finds herself a patient in the same facility where she once treated others, and finds that her claims of innocence and sanity do little to convince Dr. Pete Graham ( Robert Downey Jr. ), the psychologist assigned to her case. Gothika marked the American debut of acclaimed and controversial French filmmaker Mathieu Kassovitz . — Mark Deming