MacGruber (Will Forte) is one of the most decorated American hero's in history, having won a number of purple hearts, Congressional Medals of Honor, and many more recognitions. When his fiancee was killed 10 years ago, MacGruber decided to make a change to his life - no more fighting crime or disarming weapons, both of which he was very talented at. However, he is called back into the mix when his old enemy, Dieter Von Cunth (Val Kilmer) steals a nuclear warhead. MacGruber assembles a team to help him find Von Cunth, including Lt. Dixon Piper (Ryan Phillippe) and Vicki St. Elmo (Kristen Wiig), and they are on a mission to hunt down Von Cunth and disarm his dangerous weapon.