After an argument with her parents Theresa Russo (Maria Canals-Barrera) and Jerry Russo (David DeLuise) about using magic recklessly, difficult rebel teenager and budding wizard Alex Russo (Selena Gomez) makes the ultimate spell. The family of wizards is broken apart when Alex wishes her parents never met, and now she faces the likelihood that she has wished her brothers Justin Russo (David Henrie) and Max Russo (Jake T. Austin) out of existence. They must go on a frantic search for a magical stone that can undo the destructive use of magical powers before the children of the wizards find themselves cast into limbo, having never existed. The sibling rivalries must be contained to save the family unit.