Squad leader Darwin (Sam Rockwell), Weapons expert Blaster (Tracy Morgan), Martial artist pro Juarez (Penelope Cruz), Reconnaissance expert Mooch and Information specialist Speckles (Nicholas Cage), are guinea pigs that have been trained by the government to take on missions. They have the most difficult mission of trying to stop a billionaire from taking over the world with his household appliances. Darwin is constantly trying to be in charge while Blaster keeps testing him and making him feel inadequate. The game is on and the best team for the job is on the case. They have to save the world and keep their sanity while doing it.