Dominic Toretto (Vin Diesel) and Letty (Michelle Rodriguez) have not quit their old job even now when they are in the Dominican Republic. With a new gang, they continue their work of robbing the convoys of gasoline tanks while they are on the road. Meanwhile, Brian O'Conner (Paul Walker) became a federal agent. But when a crime brings Toretto an Brian back in Los Angeles, the two become friends once again on the streets where it all began. They have a mutual enemy in the form of a big drug dealer from Latin America. Their roads come across the roads and tunnels from the international borders, and the only way of revenge is to overcome the limits behind the steering wheel.